PEG MGF（10 VIALS/BOX）

Product Details

PEG MGF is a PEGylated variant of Mechano Growth Factor, a muscle-specific splice isoform of IGF-1 (IGF-1Ec) that is released in response to mechanical stress. The covalently linked polyethylene glycol significantly prolongs the half-life in research models compared to native MGF.

The PEG MGF lyophilisate is produced under controlled conditions and analyzed for purity and degree of PEGylation.

Research Relevance

• Satellite cell activation — research into the role of the MGF C-terminal fragment in muscle repair.
• Mechano-transduction — models involving mechanical loading and local growth factor signaling.
• Extended half-life — PEGylation makes long-term in vitro studies practically feasible (native MGF has a half-life of minutes).
• Comparison with IGF-1 — investigation of isoform-specific effects within the IGF-1 gene family.

Independently tested by Janoshik Independent Peptide Analytics for purity, heavy metals, and endotoxins.

Frequently Asked Questions

What is PEG MGF?
PEG MGF is a PEGylated version of Mechano Growth Factor—a muscle-specific splice isoform of IGF-1 (IGF-1Ec). The C-terminal 24-amino acid fragment is covalently linked to polyethylene glycol for enhanced stability.

What purity is guaranteed?
Janoshik validates each batch for HPLC purity ≥ 99%, with additional analysis for heavy metals and endotoxins.

How should PEG MGF be stored?
Store the lyophilisate refrigerated (2–8 °C), protected from light and moisture. Do not open vials until immediately before reconstitution.

Disclaimer: For laboratory and research purposes only. Not intended for human consumption.