Mazdutide（10 VIALS/BOX）

Product Details

Mazdutide (onderzoekscodes IBI362 en LY3305677) is een synthetisch peptide-analoog van het darmhormoon oxyntomoduline. Anders dan enkelvoudige GLP-1-agonisten activeert Mazdutide zówel de GLP-1-receptor (eetlust, maaglediging) áls de glucagonreceptor (energieverbruik). Een vetzuurketen (fatty-acyl) verlengt de halfwaardetijd, wat in onderzoek wekelijkse dosering mogelijk maakt.

Het Mazdutide-lyofilisaat wordt geleverd als research-grade peptide met een opgegeven zuiverheid van ≥ 99 %.

Specifications

Research relevance

• Dual incretin action — simultaneous activation of GLP-1R and GCGR in metabolic models.
• Energy balance — reduced appetite combined with increased energy expenditure.
• Obesity research — preclinical and clinical studies on weight loss.
• Glucose homeostasis — models related to insulin sensitivity and liver lipids.

Frequently Asked Questions

What is Mazdutide?
Mazdutide (IBI362 / LY3305677) is a synthetic oxyntomodulin analog that acts as a dual agonist on the GLP-1 and glucagon receptors.

How does it differ from a standard GLP-1?
A single GLP-1 agonist primarily suppresses appetite. Mazdutide adds glucagon receptor activation, which has been shown in studies to increase energy expenditure—a dual mechanism.

What does the fatty acyl chain do?
In research models, the fatty acid chain binds to albumin, which prolongs the half-life and allows for less frequent dosing.

How should Mazdutide be stored?
Store the lyophilisate refrigerated (2–8 °C), protected from light and moisture. Open vials only immediately before reconstitution.

Disclaimer: For laboratory and research purposes only. Not intended for human consumption.